The accuracy of self-reported smoking status assessed by cotinine test strips

We evaluated a new cotinine test strip to assess smoking status. Urine cotinine was measured using cotinine test strips and also by gas chromatographic techniques (GC) (as the reference criterion). Smoking status was assessed with a self-administered questionnaire. The cotinine test strip identified...

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Bibliographic Details
Published in:Nicotine & tobacco research 2002-08, Vol.4 (3), p.305-309
Main Authors: Parker, Donna R., Lasater, Thomas M., Windsor, Richard, Wilkins, Jeff, Upegui, David I., Heimdal, James
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Cotinine - urine
Female
Humans
Male
Medical sciences
Reagent Strips - administration & dosage
Self-Assessment
Sensitivity and Specificity
Smoking
Tobacco Use Disorder - diagnosis
Tobacco, tobacco smoking
Toxicology
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Summary:We evaluated a new cotinine test strip to assess smoking status. Urine cotinine was measured using cotinine test strips and also by gas chromatographic techniques (GC) (as the reference criterion). Smoking status was assessed with a self-administered questionnaire. The cotinine test strip identified smokers with a very high level of agreement (97.3% using 100 ng/ml and 97.1% using 250 ng/ml for the cutoff point) and non-smokers with a fair-to-moderate level of agreement (74.5% using 100 ng/ml and 86.4% using 250 ng/ml for the cutoff point). These data suggest that the cotinine test strip appears to provide a reasonably accurate measure of smoking status. Since this was the first study to evaluate the cotinine test strip using the test strip prototype, larger clinical trials are needed to evaluate the validity of the cotinine test strip compared to GC measurements to confirm smoking status.
ISSN:1462-2203
1469-994X
DOI:10.1080/14622200210142715