Levels of serum vitamin D and calcium in pregnancies complicated with fetal congenital diaphragmatic hernia and normal pregnancies

Objective: Vitamin D (VD) deficiency is a common public health problem worldwide in all age groups. Receptors and enzymes related to VD metabolism have been shown in many cells and tissues of the body. VD plays a crucial role in cellular growth and differentiation during embryogenesis. It has been s...

Full description

Saved in:
Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2017-04, Vol.30 (8), p.990-994
Main Authors: Turkmen, Gulenay Gencosmanoglu, Timur, Hakan, Tokmak, Aytekin, Yilmaz, Zehra, Kirbas, Ayse, Daglar, Korkut, Sanhal, Cem Yasar, Uygur, Dilek
Format: Article
Language:English
Subjects:
Adult
Calcium
Calcium - blood
calcium-rich dietary
Case-Control Studies
congenital diagraphma hernia
Cross-Sectional Studies
Female
Hernias, Diaphragmatic, Congenital - blood
Humans
perinatal outcome
Pregnancy
Pregnancy Complications - blood
vitamin D
Vitamin D - blood
Vitamin D Deficiency - blood
Vitamin D Deficiency - complications
Young Adult
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objective: Vitamin D (VD) deficiency is a common public health problem worldwide in all age groups. Receptors and enzymes related to VD metabolism have been shown in many cells and tissues of the body. VD plays a crucial role in cellular growth and differentiation during embryogenesis. It has been suggested that VD deficiency may be associated with various diseases, and that lower maternal serum levels may be associated with adverse perinatal outcomes. In this study, we aimed to compare serum VD levels of pregnant women whose pregnancies complicated by congenital diaphragmatic hernia (CDH) with healthy pregnant women. We also evaluated perinatal outcomes of these pregnancies. Methods: Total of 77 patients was included in this prospective and cross-sectional case-controlled study. 24 pregnant women having a fetus with CDH diagnosed prenatally formed the study group, and 53 healthy pregnants were eligible for the control group. Demographics and clinical characteristics of the cases with some laboratory parameters were recorded. Perinatal outcomes were also investigated. Results: No significant differences were observed between two groups in terms of demographics and clinical features. Mean maternal serum VD levels were significantly lower in the study group than in the controls (p: 0.019). Ionized calcium and corrected calcium levels were also found to be lower in pregnant women with CDH (p 
ISSN:1476-7058
1476-4954
DOI:10.1080/14767058.2016.1196662