The role of cervical pessary and progesterone therapy in the phenomenon of placenta previa migration

Objective: This study aimed to evaluate the effects of combined management of placenta previa with the Arabin cervical pessary and progesterone. Study design: In this randomized controlled study, we followed up 217 patients with placenta previa and high risk of preterm birth. The main group (n = 81)...

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Bibliographic Details
Published in:The journal of maternal-fetal & neonatal medicine 2020-03, Vol.33 (6), p.913-919
Main Authors: Barinov, Sergey V., Shamina, Inna V., Di Renzo, Gian Carlo, Lazareva, Oksana V., Tirskaya, Yuliya I., Medjannikova, Irina V., Ledovskikh, Inna O., Klementyeva, Lyudmila L., Dudkova, Galina V.
Format: Article
Language:English
Subjects:
abnormal placental location
Arabin cervical pessary
placental migration
preterm birth
progesterone
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Summary:Objective: This study aimed to evaluate the effects of combined management of placenta previa with the Arabin cervical pessary and progesterone. Study design: In this randomized controlled study, we followed up 217 patients with placenta previa and high risk of preterm birth. The main group (n = 81) underwent combined management with the Arabin cervical pessary and progesterone; the control group (n = 136) received progesterone only. Placental migration was monitored using Doppler scanning from 24 weeks of pregnancy onwards. Results: Patients receiving the combination of the Arabin cervical pessary and progesterone had a three-fold reduced rate of bleeding during pregnancy compared with patients in the control group (11.3% versus 33.1%; p = .006). Placental migration occurred 1.8 times more often in the pessary group (48.1% versus 26.4%; p = .037), and preterm labor
ISSN:1476-7058
1476-4954
DOI:10.1080/14767058.2018.1509068