Chemical investigation of metabolites produced by an endophytic fungi Phialemonium curvatum from the leaves of Passiflora edulis

Phialemonium curvatum, an endophytic fungus isolated from the leaves of Passiflora edulis was cultured in potato dextrose broth (PDB) media and chromatographic separation of the EtOAc extract of the broth and mycelium led to the isolation of 4-hydroxybenzoic acid (1), 3-indole acetic acid (2), solan...

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Bibliographic Details
Published in:Natural product research 2018-10, Vol.32 (20), p.2483-2486
Main Authors: Rathnayake, G. R. Nalin, Kumar, N. Savitri, Jayasinghe, Lalith, Araya, Hiroshi, Fujimoto, Yoshinori
Format: Article
Language:English
Subjects:
Acetic acid
Antifungal activity
Dextrose
Endophytes
endophytic fungi
Fungi
Fungicides
Glycerol
Indoleacetic acid
Leaves
Metabolites
Organic chemistry
p-Hydroxybenzoic acid
Passiflora edulis
Phialemonium curvatum
Potatoes
Uracil
Uridine
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Summary:Phialemonium curvatum, an endophytic fungus isolated from the leaves of Passiflora edulis was cultured in potato dextrose broth (PDB) media and chromatographic separation of the EtOAc extract of the broth and mycelium led to the isolation of 4-hydroxybenzoic acid (1), 3-indole acetic acid (2), solaniol (3), uracil (4), uridine (5) and glycerol (6). Compound 2 showed a weak antifungal activity against Cladosporium cladosporioides. This is the first report of the isolation of the endophytic fungus P. curvatum from P. edulis and complete 13 CNMR assignments of 3.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2017.1416373