Solvent extraction, spectral analysis and antibacterial activity of the bioactive crystals of Sargassum aquifolium (Turner) C.Agardh from Red Sea

The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of...

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Bibliographic Details
Published in:Natural product research 2021-04, Vol.35 (8), p.1379-1383
Main Authors: Moni, Sivakumar Sivagurunathan, Alam, Mohammad Firoz, Makeen, Hafiz A., Alhazmi, Hassan A., Sultan, Muhammad, Siddiqui, Rahimullah, Jabeen, Aamena, Sanobar, Syeda, Alam, Md Shamsher, Rehman, Zia Ur, Elmobark, Mohamed Eltyep, Madkhali, Osama, Haque, Anzarul, Albratty, Mohammed
Format: Article
Language:English
Subjects:
Algae
Anti-Bacterial Agents - chemistry
Anti-Bacterial Agents - pharmacology
antibacterial
Antibacterial activity
Bacteria
Bioactive compounds
Biological activity
brown alga
Carbon-13 Magnetic Resonance Spectroscopy
Chemical composition
Chemical tests
Crude oil
Crystallization
Crystals
Escherichia coli - drug effects
Humans
Indian Ocean
Microbial Sensitivity Tests
NMR
Nuclear magnetic resonance
Petroleum
Petroleum ether
phyto constituents
Proton Magnetic Resonance Spectroscopy
Red sea
saponins
Sargassum
Sargassum - chemistry
Seaweed - chemistry
Seaweeds
Solvent extraction
Solvents - chemistry
Spectral analysis
Spectroscopy, Fourier Transform Infrared
Spectrum analysis
tannins
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Summary:The purpose of this study was to investigate the chemical composition and anti-bacterial properties of the bioactive principles of Sargassum aquifolium (Turner) C.Agardh, a brown seaweed in Red sea of Jazan province, Kingdom of Saudi Arabia. Crystals were obtained from the petroleum ether extract of Sargassum aquifolium and subjected to chemical tests, FTIR spectroscopic analysis and NMR analysis to identify their chemical composition, and to study their antibacterial properties against selected human pathogenic bacteria. In addition, GC-MS analysis was performed to identify the bioactive compounds in the crude petroleum ether extract. Results of the antibacterial effect of the crystal analyte showed a wide spectrum of activity against the screened human pathogenic bacteria.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2019.1645659