Govanoside B, a new steroidal saponin from rhizomes of Trillium govanianum

Trillium govanianum, commonly known as Nag Chhatri and Teen Patra, is a popular herbal supplement traditionally used for curing different inflammatory and sexual disorders, infection and wound healing. Steroidal saponins are considered as active components of this species. The present study demonstr...

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Bibliographic Details
Published in:Natural product research 2022-01, Vol.36 (1), p.37-45
Main Authors: Singh, Prithvi Pal, Suresh, Patil Shivprasad, Bora, Prateek Singh, Bhatt, Vinod, Sharma, Upendra
Format: Article
Language:English
Subjects:
Rhizome - chemistry
Saponins - isolation & purification
Saponins - pharmacology
steroidal saponin
Steroids - isolation & purification
Steroids - pharmacology
structure elucidation
Trillium - chemistry
Trillium govanianum
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Summary:Trillium govanianum, commonly known as Nag Chhatri and Teen Patra, is a popular herbal supplement traditionally used for curing different inflammatory and sexual disorders, infection and wound healing. Steroidal saponins are considered as active components of this species. The present study demonstrated the isolation of nine steroidal saponins, including one new compound named as govanoside B (9) and eight known, pregna-chacotrioside (1), pennogenin-triglycoside (2), borassoside E (3), pennogenin-tetraglycoside (4), protodioscin (5), clintonioside B (6), pennogenin-diglycoside (7) and borassoside D (8). This is the first report on the isolation of 1, 2, 4, 5, 6, 7 and 8 from rhizomes of T. govanianum. The extract, fractions and isolated compounds were further evaluated for their DPPH and ABTS radical scavenging activity.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786419.2020.1761360