Topical chlormethine hydrochloride causing bullous reaction

We describe a woman misusing chlormethine hydrochloride lotion for vitiligo with dermatological complications of local urticarial and bullous reactions. Presentations, complications, and management of topical chlormethine hydrochloride overdose are discussed. Surface decontamination and follow-up fo...

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Bibliographic Details
Published in:Clinical toxicology (Philadelphia, Pa.) Pa.), 2009-09, Vol.47 (8), p.834-835
Main Authors: Ngai, Ka Yan, Chan, Ho Yin, Ng, Fu
Format: Article
Language:English
Subjects:
Administration, Cutaneous
Adult
Alkylating Agents - administration & dosage
Alkylating Agents - poisoning
Anti-Allergic Agents - therapeutic use
Blister - chemically induced
Blister - pathology
Blister - therapy
Chlormethine hydrochloride
Decontamination
Dermatological complications
Drug Eruptions - etiology
Drug Eruptions - pathology
Drug Eruptions - therapy
Erythema - chemically induced
Female
Humans
Mechlorethamine - administration & dosage
Mechlorethamine - poisoning
Mustard
Nonprescription Drugs - poisoning
Self Medication
Tetanus Antitoxin - therapeutic use
Treatment Outcome
Vitiligo - drug therapy
Citations: Items that this one cites
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Description
Summary:We describe a woman misusing chlormethine hydrochloride lotion for vitiligo with dermatological complications of local urticarial and bullous reactions. Presentations, complications, and management of topical chlormethine hydrochloride overdose are discussed. Surface decontamination and follow-up for potential complications are major treatments.
ISSN:1556-3650
1556-9519
DOI:10.1080/15563650903222148