Diphoterine® for Emergent Decontamination of Skin/Eye Chemical Splashes: 24 Cases

Chemical skin/eye splashes can cause burns. Standard references recommend decontamination with water. Diphoterine, a polyvalent, hypertonic, amphoteric, chelating solution is an alternative. Occupational medical records of 24 workers in a German metallurgy firm from 1994 to 1998 were reviewed. There...

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Bibliographic Details
Published in:Cutaneous and ocular toxicology 2006-01, Vol.25 (4), p.249-258
Main Authors: Nehles, Jochen, Hall, Alan H., Blomet, Joël, Mathieu, Laurence
Format: Article
Language:English
Subjects:
Accidents, Occupational
Adult
Biological and medical sciences
Burns, Chemical - etiology
Burns, Chemical - therapy
Chemical splashes
Decontamination
Decontamination - methods
Decontamination eye/skin
Diphoterine
Epidemiology. Vaccinations
Eye Burns - chemically induced
Eye Burns - therapy
General aspects
Humans
Infectious diseases
Male
Medical sciences
Middle Aged
Ophthalmic Solutions - therapeutic use
Organic Chemicals - therapeutic use
Skin - drug effects
Toxicology
Treatment Outcome
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Summary:Chemical skin/eye splashes can cause burns. Standard references recommend decontamination with water. Diphoterine, a polyvalent, hypertonic, amphoteric, chelating solution is an alternative. Occupational medical records of 24 workers in a German metallurgy firm from 1994 to 1998 were reviewed. There were 11 acid eye splashes, 8 acid skin splashes, 4 base eye splashes, and 1 base skin splash. Following Diphoterine decontamination, no burns developed and there were no requirements for burn treatment or sequelae. Three workers had 1 lost workday each. Diphoterine decontamination successfully prevented skin/eye burns in this group of metallurgy workers.
ISSN:1556-9527
1556-9535
DOI:10.1080/15569520601013160