A dynamical analysis and numerical simulation of COVID-19 and HIV/AIDS co-infection with intervention strategies

HIV/AIDS-COVID-19 co-infection is a major public health concern especially in developing countries of the world. This paper presents HIV/AIDS-COVID-19 co-infection to investigate the impact of interventions on its transmission using ordinary differential equation. In the analysis of the model, the s...

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Bibliographic Details
Published in:Journal of biological dynamics 2023-12, Vol.17 (1), p.2175920-2175920
Main Authors: Teklu, Shewafera Wondimagegnhu, Kotola, Belela Samuel
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Acquired Immunodeficiency Syndrome - epidemiology
AIDS
Cholera
co-infection
Coinfection - epidemiology
Computer Simulation
Coronaviruses
COVID-19
COVID-19 vaccines
Developing countries
Disease prevention
Disease transmission
Epidemics
HIV
Human immunodeficiency virus
Humans
Immune system
Infections
Infectious diseases
LDCs
Malaria
Mathematical models
Models, Biological
Ordinary differential equations
Pandemics
Pneumonia
protection
Public health
Reproduction
Sensitivity analysis
Simulation
Social distancing
stability analysis
treatment
Tropical diseases
Viruses
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Summary:HIV/AIDS-COVID-19 co-infection is a major public health concern especially in developing countries of the world. This paper presents HIV/AIDS-COVID-19 co-infection to investigate the impact of interventions on its transmission using ordinary differential equation. In the analysis of the model, the solutions are shown to be non-negative and bounded, using next-generation matrix approach the basic reproduction numbers are computed, sufficient conditions for stabilities of equilibrium points are established. The sensitivity analysis showed that transmission rates are the most sensitive parameters that have direct impact on the basic reproduction numbers and protection and treatment rates are more sensitive and have indirect impact to the basic reproduction numbers. Numerical simulations shown that some parameter effects on the transmission of single infections as well as co-infection, and applying the protection rates and treatment rates have effective roles to minimize and also to eradicate the HIV/AIDS-COVID-19 co-infection spreading in the community.
ISSN:1751-3758
1751-3766
DOI:10.1080/17513758.2023.2175920