Utility of serological screening for measles, mumps and rubella in immunocompromised patients

Marchi et al. in their article (Measles in pregnancy: a threat for Italian women? Hum Vaccin Immunother. 2019 Jun 20:1-3) observed that 96.9% of pregnant women were positive for anti-measles IgG (with a higher risk of contracting measles in those aged 19-29 years) emphasizing the importance of serol...

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Bibliographic Details
Published in:Human vaccines & immunotherapeutics 2019-12, Vol.15 (12), p.2854-2855
Main Authors: Sticchi, L, Astengo, M., Iavarone, I.G., Icardi, G.
Format: Article
Language:English
Subjects:
Adult
Aged
Antibodies, Viral - blood
Female
Humans
Immunocompromised Host
Italy
Italy - epidemiology
Letter
Male
Mass Screening
Measles
Measles - epidemiology
Measles - immunology
Measles-Mumps-Rubella Vaccine
Middle Aged
mumps
Mumps - epidemiology
Mumps - immunology
Odds Ratio
rubella
Rubella - epidemiology
Rubella - immunology
Seroepidemiologic Studies
Serologic Tests
vaccination
Young Adult
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Summary:Marchi et al. in their article (Measles in pregnancy: a threat for Italian women? Hum Vaccin Immunother. 2019 Jun 20:1-3) observed that 96.9% of pregnant women were positive for anti-measles IgG (with a higher risk of contracting measles in those aged 19-29 years) emphasizing the importance of serological screening before pregnancy. We evaluated seroprotection/seropositivity rates to Measles, Mumps and Rubella in 324 adults with an acquired immune-deficiency needing an immunization program. We found that younger patients (20-29 years) had a seroprevalence below 85%. Overall, a relevant proportion (21.6%, 54/250) of patients was susceptible to at least one infection needing immunization. Our results confirm the usefulness of proper strategies for identifying individuals susceptible to vaccine-preventable infections and protecting them through vaccination.
ISSN:2164-5515
2164-554X
DOI:10.1080/21645515.2019.1657353