Seroprevalence of anti-mumps virus IgG antibody titer and voluntary mumps vaccination coverage in young adults in Japan

In Japan, monovalent vaccine against mumps virus (MuV) infection was shifted to a voluntary basis vaccination due to the incidences of aseptic meningitis in the past. According to an analysis of a total of 409 participants aged 18-20 years, overall vaccination coverage rate was 48%. The mean anti-Mu...

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Bibliographic Details
Published in:Human vaccines & immunotherapeutics 2021-09, Vol.17 (9), p.3153-3155
Main Authors: Sasaki, Hiraku, Fukunaga, Tomoko, Asano, Ai, Yamanaka, Kansuke, Oikawa, Kota, Shibata, Nobuto
Format: Article
Language:English
Subjects:
Humans
IgG antibody titer
Immunoglobulin G
Japan - epidemiology
Letters
Mumps
Mumps - epidemiology
Mumps - prevention & control
Mumps Vaccine
MuV
Seroepidemiologic Studies
Vaccination
Vaccination Coverage
Young Adult
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Summary:In Japan, monovalent vaccine against mumps virus (MuV) infection was shifted to a voluntary basis vaccination due to the incidences of aseptic meningitis in the past. According to an analysis of a total of 409 participants aged 18-20 years, overall vaccination coverage rate was 48%. The mean anti-MuV IgG antibody titer of participants with medical history and more than two times vaccination was significantly higher than that in those without a medical history and unvaccinated and single vaccination, respectively. Seropositivity against MuV infection was >50% regardless of the number of vaccinations. Although these results suggest that seropositivity may persist due to asymptomatic infection, it is necessary to implement either a high vaccine coverage or routine vaccination for prevention of periodic mumps epidemics.
ISSN:2164-5515
2164-554X
DOI:10.1080/21645515.2021.1913967