Anaesthesia associated developmental neurotoxicity (AADN) 2015

The long-term cerebral effects of general anaesthesia at the extremes of age are currently enjoying attention. In children, the concern is that exposure to anaesthesia when less than 4 years of age may cause subsequent learning disabilities and behavioural changes. However, clinical equipoise exists...

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Bibliographic Details
Published in:Southern African journal of anaesthesia and analgesia 2016-01, Vol.22 (1), p.4-13
Main Authors: Ramklass, Ramona, Hauser, Neil, Levin, Andrew I
Format: Article
Language:English
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Summary:The long-term cerebral effects of general anaesthesia at the extremes of age are currently enjoying attention. In children, the concern is that exposure to anaesthesia when less than 4 years of age may cause subsequent learning disabilities and behavioural changes. However, clinical equipoise exists as the available human studies are imperfect and the results of the large-scale multinational trials are not yet available. This structured narrative review summarises the overwhelming amount of information available. Everything should be as simple as it can be, but not simpler. (Albert Einstein)
ISSN:2220-1181
2220-1173
DOI:10.1080/22201181.2015.1126980