Bioactive profile, health benefits and safety evaluation of sea buckthorn (Hippophae rhamnoides L.): A review

Sea buckthorn (Hippophae rhamnoides L.) contains a large number of versatile compounds with antioxidant and hence medical properties that have been reported from time to time. Intensive work on the medical properties of sea buckthorn has concluded incredible results like the effects on atheroscleros...

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Bibliographic Details
Published in:Cogent food & agriculture 2016-12, Vol.2 (1)
Main Authors: Wani, Touseef Ahmed, Wani, S.M., Ahmad, Mukhtar, Ahmad, Mudasir, Gani, Adil, Masoodi, F.A.
Format: Article
Language:English
Subjects:
antioxidant activity
Antioxidants
Arteriosclerosis
Atherosclerosis
Body weight
Hematology
Hippophae rhamnoides
Kidneys
Lethal dose
Liver
medical value
Organ weight
Plant extracts
Platelet aggregation
Safety
safety evaluation
Sea buckthorn
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Summary:Sea buckthorn (Hippophae rhamnoides L.) contains a large number of versatile compounds with antioxidant and hence medical properties that have been reported from time to time. Intensive work on the medical properties of sea buckthorn has concluded incredible results like the effects on atherosclerosis, anti-visceral obesity, platelet aggregation, inflammation, adverse stressful situations, and that of liver injury. Only a few studies have been conducted on the safety evaluation of the plant extract but importantly no study has deemed it unsafe for animal or human consumption till date. Considering the fact that no significant changes have been observed in organ weight/body weight ratios, of any vital organ studied (except liver and kidney in 1 g/kg and 2 g/kg body weight doses, respectively) and biochemical and hematological parameters in different animal trials with an lethal dose for 50% reduction of population (LD 50 ) of >10 g/kg when given orally, there is scope for further investigations regarding its safety in the daily diet as a protective medicine.
ISSN:2331-1932
2331-1932
DOI:10.1080/23311932.2015.1128519