Insulin-secreting β-cell neoplasia in a 7-year-old female dog, case report and review

A 7-year-old female dog presented with intermittent episodes of urinary incontinence, tremors, intermittent episodes of pelvic limb weakness and collapse, and lethargy were noticed over a period of two months. Hypoglycaemia, secondary to an insulin-secreting β-cell tumour, was suspected on the basis...

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Bibliographic Details
Published in:Cogent food & agriculture 2017-01, Vol.3 (1), p.1293467
Main Authors: Uwagie-Ero, Edwin Aihanuwa, Awasum, Cheh Augustine, Onyejiakor, Chiamaka, Odigie, Eugene Amienwanlen, Asemota, Daniel Osakpamwen
Format: Article
Language:English
Subjects:
beta cell
canine
Case reports
Complications
diabetes
Dogs
Histology
hypoglycaemia
Hypoglycemia
Insulin
Insulinoma
Lethargy
neoplasia
Pancreas
Pancreatitis
Surgery
Tremors
Tumors
Ultrasound
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Description
Summary:A 7-year-old female dog presented with intermittent episodes of urinary incontinence, tremors, intermittent episodes of pelvic limb weakness and collapse, and lethargy were noticed over a period of two months. Hypoglycaemia, secondary to an insulin-secreting β-cell tumour, was suspected on the basis of clinical signs, ultrasound and serum biochemistry. A laparotomy was then performed to remove the tumour mass. Post-surgical pancreatitis was a major complication. Histology revealed a malignant neuroendocrine neoplasia of the β-cells of the pancreas. This case review is reported to keep clinicians abreast of the canine insulinoma disorder and the complications surrounding its diagnosis and treatment.
ISSN:2331-1932
2331-1932
DOI:10.1080/23311932.2017.1293467