HPLC Determination of Piracetam in Tablets; Validation of the Method

A simple, rapid, and validated HPLC method has been developed for determination of Piracetam in film coated tablets. A Lichrospher ® (100 RP-18 column was used with a mobile phase consisting of methanol-water (5:95). Quantitative evaluation was performed at 215 nm. The HPLC method is selective, prec...

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Bibliographic Details
Published in:Journal of liquid chromatography & related technologies 2005-05, Vol.28 (9), p.1407-1416
Main Authors: Dwi Lestari, Ardhani, Tri Prasetyo, Andi, Palupi, Tini, Umayah, Evi, Yuwono, Mochammad, Indrayanto, Gunawan
Format: Article
Language:English
Subjects:
Analysis
Biological and medical sciences
General pharmacology
HPLC
Medical sciences
Pharmacology. Drug treatments
Piracetam
Tablets
Validation
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Summary:A simple, rapid, and validated HPLC method has been developed for determination of Piracetam in film coated tablets. A Lichrospher ® (100 RP-18 column was used with a mobile phase consisting of methanol-water (5:95). Quantitative evaluation was performed at 215 nm. The HPLC method is selective, precise, and accurate and can be used for routine analysis of the preparations in pharmaceutical industry quality control laboratories.
ISSN:1082-6076
1520-572X
DOI:10.1081/JLC-200054893