Oligonucleotides Containing Disaccharide Nucleosides: Synthesis, Physicochemical, and Substrate Properties

The efficient synthesis of oligonucleotides containing 2′-O- β -D-ribofuranosyl (and β -D-ribopyranosyl)nucleosides, 2′-O-α-D-arabinofuranosyl (and α-L-arabinofuranosyl)nucleosides, 2′-O- β -D-erythrofuranosylnucleosides, and 2′-O-(5′-amino-5-deoxy- β -D-ribofuranosyl)nucleosides have been developed...

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Bibliographic Details
Published in:Nucleosides, nucleotides & nucleic acids nucleotides & nucleic acids, 2003-10, Vol.22 (5-8), p.1117-1118
Main Authors: Mikhailov, S. N., Efimtseva, E. V., Ermolinsky, B. S., Bobkov, G. V., Andreeva, O. I., Golubeva, A. S., Kochetkov, S. N., Van Aerschot, A., Schepers, G., Herdewijn, P.
Format: Article
Language:English
Subjects:
Chemical synthesis
Disaccharide nucleosides
Disaccharides - chemistry
Indicators and Reagents
Nucleosides - chemistry
Oligodeoxyribonucleotides - chemical synthesis
Oligonucleotides
Oligoribonucleotides - chemical synthesis
Substrate properties
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Summary:The efficient synthesis of oligonucleotides containing 2′-O- β -D-ribofuranosyl (and β -D-ribopyranosyl)nucleosides, 2′-O-α-D-arabinofuranosyl (and α-L-arabinofuranosyl)nucleosides, 2′-O- β -D-erythrofuranosylnucleosides, and 2′-O-(5′-amino-5-deoxy- β -D-ribofuranosyl)nucleosides have been developed.
ISSN:1525-7770
1532-2335
DOI:10.1081/NCN-120022750