CONVENIENT SYNTHESIS OF NOVEL 1,3,7-TRISUBSTITUTED BICYCLO[3.3.1]NONANE DERIVATIVES

Simple and efficient synthesis of several new 1,3,7-trisubstituted bicyclo[3.3.1]nonane derivatives [e.g. 1-hydroxybicyclo[3.3.1]nonane-3,7-dicarboxylic acid (4), dimethyl ester 1-hydroxybicyclo[3.3.1]nonane-3,7-dicarboxylic acid (5), di-methyl ester-1-methoxybicyclo[3.3.1]nonane-3,7-dicarboxylic ac...

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Bibliographic Details
Published in:Synthetic communications 2002-01, Vol.32 (1), p.89-97
Main Authors: Klaić, Lada, Veljković, Jelena, Mlinarić-Majerski, Kata
Format: Article
Language:English
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Summary:Simple and efficient synthesis of several new 1,3,7-trisubstituted bicyclo[3.3.1]nonane derivatives [e.g. 1-hydroxybicyclo[3.3.1]nonane-3,7-dicarboxylic acid (4), dimethyl ester 1-hydroxybicyclo[3.3.1]nonane-3,7-dicarboxylic acid (5), di-methyl ester-1-methoxybicyclo[3.3.1]nonane-3,7-dicarboxylic acid (5a), 1-hydroxy-3,7-di(hydroxymethyl)bicyclo[3.3.1]nonane (6), 1-hydroxy-3,7-di(bromomethyl)bicyclo[3.3.1]nonane (7), 1-bromo-3,7-di(bromomethyl)bicyclo[3.3.1]nonane (8) and 1-bromo-3,7-di(cyanomethyl)bicyclo[3.3.1]nonane (9)] is described.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-120001513