High-Throughput Synthesis of Alkylbenzophenones with Indium Triflate in the Absence of Solvents Using Microwave

A series of alkylbenzophenones were rapidly and efficiently prepared from alkylbenzenes and benzoyl chlorides by Friedel-Crafts acylation catalyzed with indium triflate under solvent-free conditions by microwave heating.

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Bibliographic Details
Published in:Synthetic communications 2003-12, Vol.33 (22), p.3983-3988
Main Authors: Koshima, Hideko, Kubota, Masashi
Format: Article
Language:English
Subjects:
Alkylbenzophenones
Friedel-Crafts acylation
Indium triflates
Microwave-assisted synthesis
Solvent-free synthesis
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Description
Summary:A series of alkylbenzophenones were rapidly and efficiently prepared from alkylbenzenes and benzoyl chlorides by Friedel-Crafts acylation catalyzed with indium triflate under solvent-free conditions by microwave heating.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-120026324