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Solid-Phase One Step Synthesis of 4H,4′-Exomethylene-bis[quinazolin-2-enols]

The solid-phase one step synthesis of 4H,4′-exomethylene-bis[quinazolin-2-enols] via 1,3-dipolar cycloaddition of urea on benzylideneacetophenone using Sb(III) chloride impregnated alumina is described. The reaction provides 80-85% dimeric quniazolinenols. The process is convenient, cost-effective a...

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Bibliographic Details
Published in:Synthetic communications 2004-12, Vol.34 (10), p.1819-1823
Main Authors: Ganai, B. A., Koul, Summon, Razdan, T. K., Andotra, C. S.
Format: Article
Language:English
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Summary:The solid-phase one step synthesis of 4H,4′-exomethylene-bis[quinazolin-2-enols] via 1,3-dipolar cycloaddition of urea on benzylideneacetophenone using Sb(III) chloride impregnated alumina is described. The reaction provides 80-85% dimeric quniazolinenols. The process is convenient, cost-effective and eco-friendly.
ISSN:0039-7911
1532-2432
DOI:10.1081/SCC-120034163