A comprehensive tool for image-based generation of fetus and pregnant women mesh models for numerical dosimetry studies

Fetal dosimetry studies require the development of accurate numerical 3D models of the pregnant woman and the fetus. This paper proposes a 3D articulated fetal growth model covering the main phases of pregnancy and a pregnant woman model combining the utero-fetal structures and a deformable non-preg...

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Bibliographic Details
Published in:Physics in medicine & biology 2014-08, Vol.59 (16), p.4583-4602
Main Authors: Dahdouh, S, Varsier, N, Serrurier, A, De la Plata, J-P, Anquez, J, Angelini, E D, Wiart, J, Bloch, I
Format: Article
Language:English
Subjects:
articulated growth model
Computer Science
Computer Simulation
Diagnostic Imaging
Female
Fetal Development
Fetus - radiation effects
Humans
Image Processing
image-based fetal models
Models, Biological
numerical dosimetry
Pregnancy
Radiometry - methods
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Summary:Fetal dosimetry studies require the development of accurate numerical 3D models of the pregnant woman and the fetus. This paper proposes a 3D articulated fetal growth model covering the main phases of pregnancy and a pregnant woman model combining the utero-fetal structures and a deformable non-pregnant woman body envelope. The structures of interest were automatically or semi-automatically (depending on the stage of pregnancy) segmented from a database of images and surface meshes were generated. By interpolating linearly between fetal structures, each one can be generated at any age and in any position. A method is also described to insert the utero-fetal structures in the maternal body. A validation of the fetal models is proposed, comparing a set of biometric measurements to medical reference charts. The usability of the pregnant woman model in dosimetry studies is also investigated, with respect to the influence of the abdominal fat layer.
ISSN:0031-9155
1361-6560
DOI:10.1088/0031-9155/59/16/4583