A microcantilever-based silver ion sensor using DNA-functionalized gold nanoparticles as a mass amplifier

Silver ions have been used to sterilize many products, however, it has recently been demonstrated that silver ions can be toxic. This toxicity has been studied over many years with the lethal concentration at 10 M. Silver ions can accumulate through the food chain, causing serious health problems in...

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Bibliographic Details
Published in:Nanotechnology 2017-06, Vol.28 (24), p.245501
Main Authors: You, Juneseok, Song, Yeongjin, Park, Chanho, Jang, Kuewhan, Na, Sungsoo
Format: Article
Language:English
Subjects:
cytosine
gold nanoparticle
mass amplifier
microcantilever
silver ion
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Summary:Silver ions have been used to sterilize many products, however, it has recently been demonstrated that silver ions can be toxic. This toxicity has been studied over many years with the lethal concentration at 10 M. Silver ions can accumulate through the food chain, causing serious health problems in many species. Hence, there is a need for a commercially available silver ion sensor, with high detection sensitivity. In this work, we develop an ultra-sensitive silver ion sensor platform, using cytosine based DNA and gold nanoparticles as the mass amplifier. We achieve a lower detection limit for silver ions of 10 pM; this detection limit is one million times lower than the toxic concentration. Using our sensor platform we examine highly selective characteristics of other typical ions in water from natural sources. Furthermore, our sensor platform is able to detect silver ions in a real practical sample of commercially available drinking water. Our sensor platform, which we have termed a 'MAIS' (mass amplifier ion sensor), with a simple detection procedure, high sensitivity, selectivity and real practical applicability has shown potential as an early toxicity assessment of silver ions in the environment.
ISSN:0957-4484
1361-6528
DOI:10.1088/1361-6528/aa6d16