Radioiodine pharmacokinetics in Grave's Disease and Nodular Toxic Goiter. Simplified calculation of therapeutic activity

Existing European standard recommendations for dosimetry examination in case of thyrotoxicosis offers difficult to repeat examination protocols. The individual pharmacokinetics data of 343 patients diagnosed with Graves and Plummer disease and 133 cases with known thyroid volume are presented in the...

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Bibliographic Details
Published in:Journal of physics. Conference series 2019-03, Vol.1189 (1), p.12039
Main Authors: Trukhin, A A, Rumyantsev, PO, Sirota, Ya I, Yasuchenya, V S, Slaschuk, K Yu, Sheremeta, M S, Degtyarev, M V, Nikitaev, V G, Pronichev, A N, Polyakov, E.V.
Format: Article
Language:English
Subjects:
Dosimeters
Iodine 131
Mathematical analysis
Pharmacokinetics
Pharmacology
Statistical analysis
Toxic diseases
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Summary:Existing European standard recommendations for dosimetry examination in case of thyrotoxicosis offers difficult to repeat examination protocols. The individual pharmacokinetics data of 343 patients diagnosed with Graves and Plummer disease and 133 cases with known thyroid volume are presented in the article. The data underwent parametrical statistical analysis. As a result, two clinically reproducible methods of calculating therapeutic activity have been proposed.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1189/1/012039