Kurzichalcolactone A and B, two chalcone derivatives from Indonesian Cryptocarya

Kurzichalcolactone A (1) and B (2), two chalcone derivatives were isolated from two species of Indonesian Cryptocarya: Cryptocarya phoebeopsis and Cryptocarya morotaiense. The structures of the isolated compounds were elucidated based on the analysis of spectroscopic data, including UV, IR, NMR, and...

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Bibliographic Details
Published in:Journal of physics. Conference series 2019-12, Vol.1402 (5), p.55081
Main Authors: Kurniadewi, F, Nurjayadi, M, Kartika, I R, Hakim, E H, Juliawaty, L D, Syah, Y M
Format: Article
Language:English
Subjects:
Leukemia
Mass spectra
NMR
Nuclear magnetic resonance
Physics
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Summary:Kurzichalcolactone A (1) and B (2), two chalcone derivatives were isolated from two species of Indonesian Cryptocarya: Cryptocarya phoebeopsis and Cryptocarya morotaiense. The structures of the isolated compounds were elucidated based on the analysis of spectroscopic data, including UV, IR, NMR, and mass spectra. On biological evaluation of these compounds for their cytotoxic activity, it was found that (1) exhibited moderate inhibition activities against murine leukemia P388 cells while (2) was inactive.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/1402/5/055081