Study on the 3D BioPrinting Technology of Hydrogel Tissue Engineering scaffolds

The precision molding capability of bio-3D printing is the basis for its application in tissue engineering, and SA-Gel two-component hydrogel has been widely used in bio-3D printing manufacturing of tissue engineering scaffolds. The extrusionability of hydrogel is the key point for the printing prec...

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Bibliographic Details
Published in:Journal of physics. Conference series 2022-09, Vol.2346 (1), p.12012
Main Authors: Wang, Bao-kun, Li, Yan, He, Gao-Sheng, Zhang, Ming-Hui, Gu, Tian-Qi
Format: Article
Language:English
Subjects:
Crosslinking
Hydrogels
Physics
Rheological properties
Rheology
Scaffolds
Three dimensional printing
Tissue engineering
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Summary:The precision molding capability of bio-3D printing is the basis for its application in tissue engineering, and SA-Gel two-component hydrogel has been widely used in bio-3D printing manufacturing of tissue engineering scaffolds. The extrusionability of hydrogel is the key point for the printing precision. In this paper, starting from the concentration, ratio, rheology and cross-linking mode of hydrogel, the research ideas of “single factor independent analysis” and multi-factor comprehensive application are adopted to solve the printing accuracy. Through the research and screening of printing parameters and printing compensation technology, the accurate printing of the 1D line segment and 2D grid structure at 45°C for SA-Gel hydrogel with 2% and 8% mass respectively have been achieved.
ISSN:1742-6588
1742-6596
DOI:10.1088/1742-6596/2346/1/012012