Dipping and electrospraying for the preparation of hydroxyapatite foams for bone tissue engineering

A novel fabrication technique, a combination of slurry dipping and electrospraying, was used to produce hydroxyapatite foams as potential matrices for bone tissue engineering applications. In this study, scaffolds that were slurry dipped and electrosprayed for different time intervals were compared...

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Bibliographic Details
Published in:Biomedical materials (Bristol) 2008-06, Vol.3 (2), p.025009-025009
Main Authors: Muthutantri, Anushini I, Huang, Jie, Edirisinghe, Mohan J, Bretcanu, Oana, Boccaccini, Aldo R
Format: Article
Language:English
Subjects:
Bone Substitutes - chemistry
Compressive Strength
Durapatite - chemistry
Elasticity
Electrochemistry - methods
Gases - chemistry
Hardness
Hot Temperature
Materials Testing
Tissue Engineering - methods
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Summary:A novel fabrication technique, a combination of slurry dipping and electrospraying, was used to produce hydroxyapatite foams as potential matrices for bone tissue engineering applications. In this study, scaffolds that were slurry dipped and electrosprayed for different time intervals were compared with foams prepared by the individual methods of dipping and electrospraying. Significant differences in the distribution of cracks on the struts, the strut thickness and porosity were observed on the sintered foams prepared under the varied conditions. All the sintered structures had average porosities in the range 84-94% and desirable pore interconnections, while the combined method produced foams of uniform pore distribution, thicker struts and improved mechanical properties. Further improvement of the mechanical properties has also been achieved by altering the sintering conditions.
ISSN:1748-605X
1748-6041
1748-605X
DOI:10.1088/1748-6041/3/2/025009