Effects of La 2 O 3 contents on microstructure and properties of laser-cladded 5 wt% CaB 6 /HA bioceramic coating

• Published in: Biomedical materials (Bristol) 2022-03, Vol.17 (2), p.25007
• Main Authors: Liu, Jinjing, Long, Xin, Zhu, Hongmei, Zhu, Weihua, Chen, Zhiyong, He, Dong, Song, Nini, Wang, Xinlin
• Format: Article
• Language: English
• Subjects: Alloys - chemistry; Biocompatible Materials - chemistry; Biocompatible Materials - pharmacology; Biocompatible Materials - toxicity; Calcium Phosphates - chemistry; Cell Adhesion - drug effects; Cell Line, Tumor; Cell Survival - drug effects; Ceramics - chemistry; Ceramics - pharmacology; Ceramics - toxicity; Durapatite - chemistry; Humans; Lanthanum - chemistry; Lasers; Models, Biological; Oxides - chemistry; Titanium - chemistry
• ISSN: 1748-6041; 1748-605X
• DOI: 10.1088/1748-605X/ac4b44

In the present work, 5 wt% CaB /hydroxyapatite (HA) bioceramic coatings with different La O contents (0-0.6 wt%) have been fabricated by a laser cladding technique on Ti-6Al-4V. The effects of La O contents on microstructure and properties of the laser-cladded 5 wt% CaB /HA coatings have been carefully investigated. The results show that the microstructure is obviously refined, and the structure is relatively uniform after doping 0.2-0.4 wt% La O . As the La O content increases, the corrosion resistance are found to increase firstly and then gradually decrease. The x-rays diffraction analysis confirms that the amount of HA and TCP (calcium phosphate) in the coating reaches maximum after doping 0.2 wt% La O . The La O -doped coatings show a significantly higher bone-like apatite precipitation after immersion in simulated body fluid compared with La O -free coating. In vitro experiment also shows that 5 wt% CaB /HA bioceramic coatings with 0.2-0.4 wt% La O are more suitable for the attachment and proliferation of MG63 cells, exhibiting superior bioactivity and biocompatibility.