Clinical profile and warning sign finding in children with severe dengue and non-severe dengue

Dengue fever is one of the most important emerging vector-borne viral diseases. Approximately 500,000 out of 100 million cases develop to severe dengue infection. Patient with severe dengue (SD) can be predicted by clinical profile, laboratory and warning sign which could be saved by early intervent...

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Bibliographic Details
Published in:IOP conference series. Earth and environmental science 2018-03, Vol.125 (1), p.12038
Main Authors: Adam, A S, Pasaribu, S, Wijaya, H, Pasaribu, A P
Format: Article
Language:English
Subjects:
Bleeding
Dengue fever
Dengue hemorrhagic fever
Fever
Headache
Infections
Laboratories
Medical records
Medical research
Mucosa
Myalgia
Pain
Vector-borne diseases
Viral diseases
Warning
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Summary:Dengue fever is one of the most important emerging vector-borne viral diseases. Approximately 500,000 out of 100 million cases develop to severe dengue infection. Patient with severe dengue (SD) can be predicted by clinical profile, laboratory and warning sign which could be saved by early interventions.This was a retrospective descriptive-analytic study to investigate clinical manifestations, laboratory and warning signs ofchildren with dengue infection in Haji Adam Malik hospital during January 2014-May 2016. Through medical records, we had selected 140 cases which fulfilled research criteria.Cases were classified as SD (n=28) and NSD (n=112). Most common clinical manifestations for NSD were abdominal pain (39.3%), myalgia (39.3%), headache (37.1%), mucosal bleeding (36.4%) while for SD were shock (15.7%), mucosal bleeding (15.7%), clinical fluid accumulation (15%), shortness of breath (14.3%). SGPT >1000IU/L (5 cases), SGOT >1000IU/L (9 cases), PT (10 cases) and aPTT (16 cases) were abnormal in SD. Severe dengue was frequently found in the range of white cell count 1000-4000/L and platelet count 20,000-50,000mm/uL. Clinical manifestations, warning sign, and laboratoryfinding, were different between SD and NSD.
ISSN:1755-1307
1755-1315
DOI:10.1088/1755-1315/125/1/012038