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Fabrication of magnetite-based core-shell coated nanoparticles with antibacterial properties

We report the fabrication of biofunctionalized magnetite core sodium lauryl sulfate shell antibiotic adsorption-shell nanoparticles assembled thin coatings by matrix assisted pulsed laser evaporation for antibacterial drug-targeted delivery. Magnetite nanoparticles have been synthesized and subseque...

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Bibliographic Details
Published in:Biofabrication 2015-03, Vol.7 (1), p.015014-8
Main Authors: Grumezescu, A M, Cristescu, R, Chifiriuc, M C, Dorcioman, G, Socol, G, Mihailescu, I N, Mihaiescu, D E, Ficai, A, Vasile, O R, Enculescu, M, Chrisey, D B
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Language:English
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Summary:We report the fabrication of biofunctionalized magnetite core sodium lauryl sulfate shell antibiotic adsorption-shell nanoparticles assembled thin coatings by matrix assisted pulsed laser evaporation for antibacterial drug-targeted delivery. Magnetite nanoparticles have been synthesized and subsequently characterized by transmission electron microscopy and x-ray diffraction. The obtained thin coatings have been investigated by FTIR and scanning electron microscope, and tested by in vitro biological assays, for their influence on in vitro bacterial biofilm development and cytotoxicity on human epidermoid carcinoma (HEp2) cells.
ISSN:1758-5090
1758-5082
1758-5090
DOI:10.1088/1758-5090/7/1/015014