Nanoparticles as antiviral agents against adenoviruses

Two types of gold nanoparticles, covered with shell and located on the large nanoparticle-carrier, have been synthesized and used as antiviral agents against adenoviruses. Both antiviral effect and virucidal action of the nanoparticles have been studied. It has been shown that both types of nanopart...

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Bibliographic Details
Published in:Advances in natural sciences. Nanoscience and nanotechnology 2018-06, Vol.9 (2), p.25021
Main Authors: Lysenko, V, Lozovski, V, Lokshyn, M, Gomeniuk, Yu V, Dorovskih, A, Rusinchuk, N, Pankivska, Yu, Povnitsa, O, Zagorodnya, S, Tertykh, V, Bolbukh, Yu
Format: Article
Language:English
Subjects:
adenovirus
antiviral therapy
local-field
nanoparticle
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Summary:Two types of gold nanoparticles, covered with shell and located on the large nanoparticle-carrier, have been synthesized and used as antiviral agents against adenoviruses. Both antiviral effect and virucidal action of the nanoparticles have been studied. It has been shown that both types of nanoparticles demonstrate antiviral action. Dependence of antiviral activity of nanoparticles on their concentration has been studied. Nonmonotonic dependence of the antiviral effect on nanoparticles concentration has been observed and discussed. The antiviral action of complex nanoparticles against adenovirus is important because of low toxicity of the gold nanoparticles covered with shell and of carrier nanoparticles.
ISSN:2043-6262
2043-6254
2043-6262
DOI:10.1088/2043-6254/aac42a