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The effect of different CT scanners, scan parameters and scanning setup on Hounsfield units and calibrated bone density: a phantom study
This study investigated the effect of different CT scanners, reconstruction protocols, scan positions, and air gaps on HU and/or calibrated calcium hydroxyapatite concentrations (CaHA). Phantoms containing bone-like materials were scanned on four different CT scanners. The effect of slice thickness,...
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Published in: | Biomedical physics & engineering express 2018-08, Vol.4 (5), p.55013 |
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creator | Free, Jeffrey Eggermont, Florieke Derikx, Loes van Leeuwen, Ruud van der Linden, Yvette Jansen, Wim Raaijmakers, Esther Tanck, Esther Kaatee, Robert |
description | This study investigated the effect of different CT scanners, reconstruction protocols, scan positions, and air gaps on HU and/or calibrated calcium hydroxyapatite concentrations (CaHA). Phantoms containing bone-like materials were scanned on four different CT scanners. The effect of slice thickness, field of view (FOV) and reconstruction kernel on HU was investigated. Using clinical scan and reconstruction protocols and a calibration phantom, HU and CaHA were determined for different positions, and air gaps between phantom and calibration phantom. Changing reconstruction kernel considerably affected the HU (range −31 HU to 64 HU), whereas slice thickness and FOV did not. Inter-scanner differences in HU were |
doi_str_mv | 10.1088/2057-1976/aad66a |
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Phantoms containing bone-like materials were scanned on four different CT scanners. The effect of slice thickness, field of view (FOV) and reconstruction kernel on HU was investigated. Using clinical scan and reconstruction protocols and a calibration phantom, HU and CaHA were determined for different positions, and air gaps between phantom and calibration phantom. Changing reconstruction kernel considerably affected the HU (range −31 HU to 64 HU), whereas slice thickness and FOV did not. Inter-scanner differences in HU were <88 HU and decreased to <47 CaHA after calibration. Different positions of the phantom resulted in differences (on average up to −26 HU and −24 CaHA). An air gap of 2.5 cm atop the calibration phantom resulted in errors up to −41 CaHA. If absolute HU and calibrated CaHA are needed, different reconstruction kernels and changes in position within the FOV as well as air gaps should be avoided.</description><identifier>ISSN: 2057-1976</identifier><identifier>EISSN: 2057-1976</identifier><identifier>DOI: 10.1088/2057-1976/aad66a</identifier><identifier>CODEN: NJOPFM</identifier><language>eng</language><publisher>IOP Publishing</publisher><subject>calcium hydroxyapatite ; CT protocols ; CT scanner ; Hounsfield units ; inter-scanner differences</subject><ispartof>Biomedical physics & engineering express, 2018-08, Vol.4 (5), p.55013</ispartof><rights>2018 IOP Publishing Ltd</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c378t-d15252e4d6ee89b7a149aa4a5ef4a1dee270a56b2fc98aa3163c58c788e63fa73</citedby><cites>FETCH-LOGICAL-c378t-d15252e4d6ee89b7a149aa4a5ef4a1dee270a56b2fc98aa3163c58c788e63fa73</cites><orcidid>0000-0002-1573-2613</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids></links><search><creatorcontrib>Free, Jeffrey</creatorcontrib><creatorcontrib>Eggermont, Florieke</creatorcontrib><creatorcontrib>Derikx, Loes</creatorcontrib><creatorcontrib>van Leeuwen, Ruud</creatorcontrib><creatorcontrib>van der Linden, Yvette</creatorcontrib><creatorcontrib>Jansen, Wim</creatorcontrib><creatorcontrib>Raaijmakers, Esther</creatorcontrib><creatorcontrib>Tanck, Esther</creatorcontrib><creatorcontrib>Kaatee, Robert</creatorcontrib><title>The effect of different CT scanners, scan parameters and scanning setup on Hounsfield units and calibrated bone density: a phantom study</title><title>Biomedical physics & engineering express</title><addtitle>BPEX</addtitle><addtitle>Biomed. Phys. Eng. Express</addtitle><description>This study investigated the effect of different CT scanners, reconstruction protocols, scan positions, and air gaps on HU and/or calibrated calcium hydroxyapatite concentrations (CaHA). Phantoms containing bone-like materials were scanned on four different CT scanners. The effect of slice thickness, field of view (FOV) and reconstruction kernel on HU was investigated. Using clinical scan and reconstruction protocols and a calibration phantom, HU and CaHA were determined for different positions, and air gaps between phantom and calibration phantom. Changing reconstruction kernel considerably affected the HU (range −31 HU to 64 HU), whereas slice thickness and FOV did not. Inter-scanner differences in HU were <88 HU and decreased to <47 CaHA after calibration. Different positions of the phantom resulted in differences (on average up to −26 HU and −24 CaHA). An air gap of 2.5 cm atop the calibration phantom resulted in errors up to −41 CaHA. If absolute HU and calibrated CaHA are needed, different reconstruction kernels and changes in position within the FOV as well as air gaps should be avoided.</description><subject>calcium hydroxyapatite</subject><subject>CT protocols</subject><subject>CT scanner</subject><subject>Hounsfield units</subject><subject>inter-scanner differences</subject><issn>2057-1976</issn><issn>2057-1976</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp1kDFPwzAQhSMEElXpzuiNpaF2EjsOG6qAIlViKbN1ic_UVetEtiPRf8DPJiUIMcB0T3fvPZ2-JLlm9JZRKRcZ5WXKqlIsALQQcJZMflbnv_RlMgthRyllIhOi4pPkY7NFgsZgE0lriLaD9OgiWW5IaMA59GH-pUgHHg4YhwUBp8erdW8kYOw70jqyansXjMW9Jr2zcbQ1sLe1h4ia1K1DotEFG493BEi3BRfbAwmx18er5MLAPuDse06T18eHzXKVrl-enpf367TJSxlTzXjGMyy0QJRVXQIrKoACOJoCmEbMSgpc1JlpKgmQM5E3XDallChyA2U-TejY2_g2BI9Gdd4ewB8Vo-oEU51oqRMtNcIcIjdjxLad2rW9d8ODqu7wXRWKK8o5ZbnqtBmc8z-c_xZ_AoWEhk8</recordid><startdate>20180807</startdate><enddate>20180807</enddate><creator>Free, Jeffrey</creator><creator>Eggermont, Florieke</creator><creator>Derikx, Loes</creator><creator>van Leeuwen, Ruud</creator><creator>van der Linden, Yvette</creator><creator>Jansen, Wim</creator><creator>Raaijmakers, Esther</creator><creator>Tanck, Esther</creator><creator>Kaatee, Robert</creator><general>IOP Publishing</general><scope>AAYXX</scope><scope>CITATION</scope><orcidid>https://orcid.org/0000-0002-1573-2613</orcidid></search><sort><creationdate>20180807</creationdate><title>The effect of different CT scanners, scan parameters and scanning setup on Hounsfield units and calibrated bone density: a phantom study</title><author>Free, Jeffrey ; Eggermont, Florieke ; Derikx, Loes ; van Leeuwen, Ruud ; van der Linden, Yvette ; Jansen, Wim ; Raaijmakers, Esther ; Tanck, Esther ; Kaatee, Robert</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c378t-d15252e4d6ee89b7a149aa4a5ef4a1dee270a56b2fc98aa3163c58c788e63fa73</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>calcium hydroxyapatite</topic><topic>CT protocols</topic><topic>CT scanner</topic><topic>Hounsfield units</topic><topic>inter-scanner differences</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Free, Jeffrey</creatorcontrib><creatorcontrib>Eggermont, Florieke</creatorcontrib><creatorcontrib>Derikx, Loes</creatorcontrib><creatorcontrib>van Leeuwen, Ruud</creatorcontrib><creatorcontrib>van der Linden, Yvette</creatorcontrib><creatorcontrib>Jansen, Wim</creatorcontrib><creatorcontrib>Raaijmakers, Esther</creatorcontrib><creatorcontrib>Tanck, Esther</creatorcontrib><creatorcontrib>Kaatee, Robert</creatorcontrib><collection>CrossRef</collection><jtitle>Biomedical physics & engineering express</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Free, Jeffrey</au><au>Eggermont, Florieke</au><au>Derikx, Loes</au><au>van Leeuwen, Ruud</au><au>van der Linden, Yvette</au><au>Jansen, Wim</au><au>Raaijmakers, Esther</au><au>Tanck, Esther</au><au>Kaatee, Robert</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The effect of different CT scanners, scan parameters and scanning setup on Hounsfield units and calibrated bone density: a phantom study</atitle><jtitle>Biomedical physics & engineering express</jtitle><stitle>BPEX</stitle><addtitle>Biomed. Phys. Eng. Express</addtitle><date>2018-08-07</date><risdate>2018</risdate><volume>4</volume><issue>5</issue><spage>55013</spage><pages>55013-</pages><issn>2057-1976</issn><eissn>2057-1976</eissn><coden>NJOPFM</coden><abstract>This study investigated the effect of different CT scanners, reconstruction protocols, scan positions, and air gaps on HU and/or calibrated calcium hydroxyapatite concentrations (CaHA). Phantoms containing bone-like materials were scanned on four different CT scanners. The effect of slice thickness, field of view (FOV) and reconstruction kernel on HU was investigated. Using clinical scan and reconstruction protocols and a calibration phantom, HU and CaHA were determined for different positions, and air gaps between phantom and calibration phantom. Changing reconstruction kernel considerably affected the HU (range −31 HU to 64 HU), whereas slice thickness and FOV did not. Inter-scanner differences in HU were <88 HU and decreased to <47 CaHA after calibration. Different positions of the phantom resulted in differences (on average up to −26 HU and −24 CaHA). An air gap of 2.5 cm atop the calibration phantom resulted in errors up to −41 CaHA. If absolute HU and calibrated CaHA are needed, different reconstruction kernels and changes in position within the FOV as well as air gaps should be avoided.</abstract><pub>IOP Publishing</pub><doi>10.1088/2057-1976/aad66a</doi><tpages>12</tpages><orcidid>https://orcid.org/0000-0002-1573-2613</orcidid></addata></record> |
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source | Institute of Physics |
subjects | calcium hydroxyapatite CT protocols CT scanner Hounsfield units inter-scanner differences |
title | The effect of different CT scanners, scan parameters and scanning setup on Hounsfield units and calibrated bone density: a phantom study |
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