RESPIRATORY DEPRESSION FOLLOWING THE USE OF TACRINE AND SUXAMETHONIUM

A case of prolonged respiratory depression following the use of tacrine and suxamethonium is described in a patient having normal pseudocholinesterase levels. The phase II block which developed was successfully treated by neostigmine. It is suggested that the patient may have been abnormally sensiti...

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Bibliographic Details
Published in:British journal of anaesthesia : BJA 1966-06, Vol.38 (6), p.487-489
Main Authors: OLDER, PAUL O., HARRIS, JOHN M., MITCHARD, MERVYN
Format: Article
Language:English
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Summary:A case of prolonged respiratory depression following the use of tacrine and suxamethonium is described in a patient having normal pseudocholinesterase levels. The phase II block which developed was successfully treated by neostigmine. It is suggested that the patient may have been abnormally sensitive to the anticholine acetylase action of the tacrine.
ISSN:0007-0912
1471-6771
DOI:10.1093/bja/38.6.487