559 An analysis of myocardial efficiency in patients with severe asymptomatic mitral regurgitation

Abstract Funding Acknowledgements None declared. Background and Aims It is difficult to determine left ventricular systolic performance in patients with severe mitral regurgitation (MR) since left ventricular ejection fraction (EF) could be preserved until the end stages of the disease. Myocardial e...

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Bibliographic Details
Published in:European heart journal cardiovascular imaging 2020-01, Vol.21 (Supplement_1)
Main Authors: Cetin Guvenc, R, Arugaslan, E, Guvenc, T S, Ozpamuk Karadeniz, F, Kasikcioglu, H, Cam, N
Format: Article
Language:English
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Summary:Abstract Funding Acknowledgements None declared. Background and Aims It is difficult to determine left ventricular systolic performance in patients with severe mitral regurgitation (MR) since left ventricular ejection fraction (EF) could be preserved until the end stages of the disease. Myocardial efficiency describes the amount of external work (EW) done by the left ventricle per unit of oxygen consumed (mVO2). In the present study, we aimed to investigate MEf in patients with asymptomatic severe MR using a novel echocardiographic method. Methods: A total of 27 patients with severe asymptomatic MR and 26 healthy volunteers were included in this cross-sectional study. EW was measured using stroke volume and blood pressure, while mVO2 was estimated using double product and LV mass. Results: There were no differences between the groups with regards to EF (66%±5% vs. 69%±7%), while MEf was significantly reduced in patients with severe MR (25%±11% vs. 44%±12%, p 
ISSN:2047-2404
2047-2412
DOI:10.1093/ehjci/jez319.289