Bioprinting technology and its applications

Bioprinting technology has emerged as a powerful tool for building tissue and organ structures in the field of tissue engineering. This technology allows precise placement of cells, biomaterials and biomolecules in spatially predefined locations within confined three-dimensional (3D) structures. Var...

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Bibliographic Details
Published in:European journal of cardio-thoracic surgery 2014-09, Vol.46 (3), p.342-348
Main Authors: Seol, Young-Joon, Kang, Hyun-Wook, Lee, Sang Jin, Atala, Anthony, Yoo, James J.
Format: Article
Language:English
Subjects:
Bioprinting
Cells, Cultured
Humans
Regenerative Medicine
Tissue Engineering
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Summary:Bioprinting technology has emerged as a powerful tool for building tissue and organ structures in the field of tissue engineering. This technology allows precise placement of cells, biomaterials and biomolecules in spatially predefined locations within confined three-dimensional (3D) structures. Various bioprinting technologies have been developed and utilized for applications in life sciences, ranging from studying cellular mechanisms to constructing tissues and organs for implantation, including heart valve, myocardial tissue, trachea and blood vessels. In this article, we introduce the general principles and limitations of the most widely used bioprinting technologies, including jetting- and extrusion-based systems. Application-based research focused on tissue regeneration is presented, as well as the current challenges that hamper clinical utility of bioprinting technology.
ISSN:1010-7940
1873-734X
DOI:10.1093/ejcts/ezu148