How disturbing are side effects of beta blockers

Drug side effects are notoriously difficult to evaluate accurately. In this particular context there are further problems arising from the exclusion of many patients in some of the few published series of populations exposed to beta-blocking drugs. In some of these same series, placebo side effects...

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Bibliographic Details
Published in:European heart journal 1983-07, Vol.4 (suppl-D), p.143-145
Main Author: Besterman, E M
Format: Article
Language:English
Subjects:
Adrenergic beta-Antagonists - adverse effects
beta-blocking drugs
Bradycardia - chemically induced
Bronchial Spasm - chemically induced
complications
Fatigue - chemically induced
Female
Humans
Hypotension - chemically induced
Hypothermia - chemically induced
Male
Mental Disorders - chemically induced
Muscular Diseases - chemically induced
Raynaud Disease - chemically induced
Sexual Dysfunction, Physiological - chemically induced
Side effects
Substance Withdrawal Syndrome - etiology
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Summary:Drug side effects are notoriously difficult to evaluate accurately. In this particular context there are further problems arising from the exclusion of many patients in some of the few published series of populations exposed to beta-blocking drugs. In some of these same series, placebo side effects appear to affect almost as manv patients as the active drug. However, detailed breakdown of these side effects show significant differences in the actual complaints made by patients of each group. Apart from the well known major complications of beta-blocking drugs, the lesser but still disturbing ones to mention include generalized fatigue, muscle weakness, cold extremities, nightmares and impotence. A change of beta-blocking preparation or else lowering the dosage often ameliorates these problems.
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/4.suppl_D.143