4308Lung ultrasound guided dry-weight probing reduces left and right atrial dimensions and left ventricular filling pressures in hemodialysis patients with hypertension

• Published in: European heart journal 2019-10, Vol.40 (Supplement_1)
• Main Authors: Loutradis, C, Papadopoulos, C E, Sachpekidis, V, Pagourelias, E, Ekart, R, Krunic, B, Toumpourleka, M, Tsouchnikas, I, Vassilikos, V, Papagianni, A, Zoccali, C, Sarafidis, P A
• Format: Article
• Language: English
• ISSN: 0195-668X; 1522-9645
• DOI: 10.1093/eurheartj/ehz745.0153

Abstract Introduction and purpose Left ventricular hypertrophy and dysfunction is tightly associated with adverse outcome in hemodialysis. Hypertension and increased preload due to hypervolemia are major factors for these cardiac anomalies in hemodialysis. This study examined the effect of lung-ultrasound-guided dry-weight reduction on echocardiographic indices of left and right cardiac size, systolic and diastolic function in hypertensive hemodialysis patients. Methods This pilot, single-blind trial randomised 71 clinically euvolemic hypertensive hemodialysis patients in an active group (n=35), following a strategy for dry-weight reduction guided by the total number of US-B lines (US-B lines score) prior to a mid-week dialysis session, and a control group (n=36), following standard-of-care treatment. Among others, patients underwent two-dimensional and tissue-Doppler echocardiographic (TDI) at baseline and after 8-weeks. Results Overall, 19 (54.3%) patients in the active and 5 (13.9%) in the control group had UF intensification (p