P2611The prognostic value of serum magnesium levels in patients with heart failure with preserved left ventricular ejection fraction

Abstract Background In heart failure (HF) patients, various factors, such as hyperactivity of the renin-angiotensin system, influence of drug therapy such as loop and thiazide diuretics, undernutrition and others, can causes hypokalemia and hypomagnesemia. Although serum magnesium (Mg) levels are cl...

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Published in:European heart journal 2019-10, Vol.40 (Supplement_1)
Main Authors: Nishihara, T, Sueta, D, Yamamoto, E, Fujisue, K, Usuku, H, Oike, F, Takae, M, Takashio, S, Sakamoto, K, Kaikita, K, Tsujita, K
Format: Article
Language:English
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Summary:Abstract Background In heart failure (HF) patients, various factors, such as hyperactivity of the renin-angiotensin system, influence of drug therapy such as loop and thiazide diuretics, undernutrition and others, can causes hypokalemia and hypomagnesemia. Although serum magnesium (Mg) levels are closely associated with the prognosis of HF patients, the clinical significance of serum Mg levels in cardiovascular outcomes of HF with preserved ejection fraction (HFpEF) patients is not fully understood. Purpose We examined the relationship between serum Mg and future HF-related events in patients with HFpEF. Methods This study was a retrospective, single-center, observational study. We enrolled 452 consecutive HFpEF patients admitted to our university hospital between January 2007 and September 2013 and followed them for 4 years or until occurrence of HF-related events. We defined lower serum Mg as
ISSN:0195-668X
1522-9645
DOI:10.1093/eurheartj/ehz748.0935