Atrial fibrillation burden: an update—the need for a CHA2DS2-VASc-AFBurden score

Abstract Atrial fibrillation (AF) is an established independent risk factor for stroke. Current guidelines regard AF as binary; either present or absent, with the decision for anti-coagulation driven by clinical variables alone. However, there are increasing data to support a biological gradient of...

Full description

Saved in:
Bibliographic Details
Published in:Europace (London, England) England), 2021-05, Vol.23 (5), p.665-673
Main Authors: Tiver, Kathryn D, Quah, Jing, Lahiri, Anandaroop, Ganesan, Anand N, McGavigan, Andrew D
Format: Article
Language:English
Citations: Items that this one cites
Items that cite this one
Online Access:Request full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Abstract Atrial fibrillation (AF) is an established independent risk factor for stroke. Current guidelines regard AF as binary; either present or absent, with the decision for anti-coagulation driven by clinical variables alone. However, there are increasing data to support a biological gradient of AF burden and stroke risk, both in clinical and non-clinical AF phenotypes. As such, this raises the concept of combining AF burden assessment with a clinical risk score to refine and individualize the assessment of stroke risk in AF—the CHA2DS2VASc-AFBurden score. We review the published data supporting a biological gradient to try and construct a putative schema of risk attributable to AF burden.
ISSN:1099-5129
1532-2092
DOI:10.1093/europace/euaa287