Hypothermia in Experimental Infections: I. Preliminary Observations on Tolerance of Guinea Pigs and Rabbits to Induced Hypothermia

A technic has been developed whereby rabbits and guinea pigs can be subjected to prolonged hypothermia of 8 to 10 C. A convenient method of temperature measurement and control of as many as 10 animals simultaneously has been described. Rabbits have been found to tolerate continuous hypothermia of 8...

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Bibliographic Details
Published in:The Journal of infectious diseases 1943-05, Vol.72 (3), p.179-182
Main Authors: Hardy, James D., Duerschner, Dorothy Rhoades, Muschenheim, Carl
Format: Article
Language:English
Subjects:
Anesthetics
Body temperature
Dosage
Galvanometers
Hypothermia
Infections
Refrigerators
Temperature gradients
Thermocouples
Thermometers
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Summary:A technic has been developed whereby rabbits and guinea pigs can be subjected to prolonged hypothermia of 8 to 10 C. A convenient method of temperature measurement and control of as many as 10 animals simultaneously has been described. Rabbits have been found to tolerate continuous hypothermia of 8 to 10 C. for periods as long as 96 hours. Guinea pigs do not well tolerate continuous hypothermia for periods longer than 24 hours but may be subjected to periods of 24 hours or less, repeatedly, over many weeks.
ISSN:0022-1899
1537-6613
DOI:10.1093/infdis/72.3.179