Management of severe systemic infections caused by multiple resistant organisms

Fifty-two patients suffering from infections caused by multi-resistant bacteria were treated with cefotaxime. Twenty-six had urinary tract infection, 12 septicaemia, 8 respiratory tract infection, 6 meningitis, 1 endocarditis, 1 soft tissue infection, and 1 typhoid fever. Three patients had dual inf...

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Bibliographic Details
Published in:Journal of antimicrobial chemotherapy 1980-01, Vol.6 (suppl-A), p.269-272
Main Authors: Shah, Pramod M., Helm, Eilke B., Stille, Wolfgang
Format: Article
Language:English
Subjects:
Bacterial Infections - drug therapy
Bacterial Infections - microbiology
Cefotaxime
Cephalosporins - adverse effects
Cephalosporins - therapeutic use
Drug Resistance, Microbial
Female
Humans
Male
Meningitis - drug therapy
Respiratory Tract Infections - drug therapy
Sepsis - drug therapy
Urinary Tract Infections - drug therapy
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Summary:Fifty-two patients suffering from infections caused by multi-resistant bacteria were treated with cefotaxime. Twenty-six had urinary tract infection, 12 septicaemia, 8 respiratory tract infection, 6 meningitis, 1 endocarditis, 1 soft tissue infection, and 1 typhoid fever. Three patients had dual infections. Treatment was successful in 39 patients, including one with endocarditis, and another with meningitis caused by a highly resistant Klebsiella pneumoniae strain. The patient with typhoid fever failed to respond to cefotaxime. There were few side-effects apart from 4 patients who developed rashes.
ISSN:0305-7453
1460-2091
DOI:10.1093/jac/6.suppl_A.269