Brief Communication: Ultrastructural Study of Herpes Simplex Virus Infection of Mouse Cells Chronically Producing Rauscher Leukemia Virus

Mouse cells (JLSV9) chronically infected with Rauscher leukemia virus (JLSV9-RLV) were superinfected with low multiplicities of herpes simplex virus subtype-1 (HSV-1) and examined by electron microscopy 12 and 24 hours after infection. In several cells, both viruses were observed in various stages o...

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Bibliographic Details
Published in:JNCI : Journal of the National Cancer Institute 1974-10, Vol.53 (4), p.1169-1173
Main Authors: Andrese, Angelo P., Vande Woude, George F., Walling, Mary Jane
Format: Article
Language:English
Online Access:Get full text
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Summary:Mouse cells (JLSV9) chronically infected with Rauscher leukemia virus (JLSV9-RLV) were superinfected with low multiplicities of herpes simplex virus subtype-1 (HSV-1) and examined by electron microscopy 12 and 24 hours after infection. In several cells, both viruses were observed in various stages of development. Many double-enveloped herpes-like particles were seen in the superinfected JLSV9-RLV cultures but not in JLSV9 control cells infected with HSV-1 alone.
ISSN:0027-8874
1460-2105
DOI:10.1093/jnci/53.4.1169