The Treatment of Uraemic Hyperphosphataemia with Calcium Acetate and Calcium Carbonate: A Comparative Study

A comparative study of long-term haemodialysis patients investigated the effects of calcium acetate and calcium carbonate on concentrations of serum phosphate, calcium, and parathyroid hormone. It was demonstrated that both substances led to a significant decrease in phosphate and serum parathyroid...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1991, Vol.6 (3), p.170-175
Main Authors: Schaefer, K., Scheer, Jutta, Asmus, G., Umlauf, Ellen, Hagemann, J., von Herrath, D.
Format: Article
Language:English
Subjects:
Acetates - administration & dosage
Acetates - therapeutic use
Acetic Acid
Biological and medical sciences
Calcitriol
Calcitriol - administration & dosage
Calcitriol - adverse effects
Calcium - blood
Calcium acetate
Calcium carbonate
Calcium Carbonate - administration & dosage
Calcium Carbonate - therapeutic use
Female
Humans
Hypercalcemia - etiology
Intestinal phosphate binder
Male
Medical sciences
Middle Aged
Parathyroid Hormone - blood
Pharmacology. Drug treatments
Phosphates - blood
Uraemic hyperphosphataemia
Uremia - blood
Uremia - drug therapy
Urinary system
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Summary:A comparative study of long-term haemodialysis patients investigated the effects of calcium acetate and calcium carbonate on concentrations of serum phosphate, calcium, and parathyroid hormone. It was demonstrated that both substances led to a significant decrease in phosphate and serum parathyroid hormone. Administration of calcium acetate reduced the serum phosphate concentration in 7 weeks from an initial value of 2.08 ± 0.53 mmol/1 to 1.51 ± 0.39 mmol/1 (P
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/6.3.170