5963 THE ASSOCIATION OF FRAILTY, DENTAL STATUS, İNFLAMMATION AND MALNUTRITION İN HEMODIALYSIS PATIENTS

Abstract Background and Aims Persistent low-grade inflammation and malnutrition in chronic kidney disease (CKD) are associated with so many CKD complications. Frailty, the state of increased vulnerability often associated with aging, had a higher incidence in CKD patients regardless of age. In this...

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Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 2023-06, Vol.38 (Supplement_1)
Main Authors: Çağlar, Tuğçe Topoğlu, Erten, Yasemin, Yıldırım, Saliha, Borazan, Funda Yıldırım, Ozkula, Handan
Format: Article
Language:English
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Summary:Abstract Background and Aims Persistent low-grade inflammation and malnutrition in chronic kidney disease (CKD) are associated with so many CKD complications. Frailty, the state of increased vulnerability often associated with aging, had a higher incidence in CKD patients regardless of age. In this study, we aimed to investigate the frequency of frailty among hemodialysis patients and volunteers with normal kidney function to define its relationship with inflammatory markers, biochemical parameters and dental status. Method A cohort of 86 CKD patients with hemodialysis (HD) and 74 volunteers with normal kidney function (similar in terms of age and gender distribution) were included in this study. Both groups were evaluated by the Clinical Frailty Scale in three groups as non-brittle, pre-frail and frail. Demographic characteristics, biochemical parameters and dental status were recorded. Results 21 of 86 patients (24.4%) were frail in CKD patients with HD, and 4 of 76 patients (5.4%) in the control group were frail (p
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/gfad063d_5963