Teratozoospermia and in-vitro fertilization: a randomized prospective study

A prospective randomized study was conducted to assess the prognostic value of sperm morphology in an in-vitro fertilization (IVF) programme, using strict criteria. The first group (T, teratozoospermic) included 32 couples with an isolated teratozoospermia in the male partner (morphology 9% normal,...

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Bibliographic Details
Published in:Human reproduction (Oxford) 1994-08, Vol.9 (8), p.1479-1484
Main Authors: Ombelet, W., Fourie, F.leR, Vandeput, H., Bosmans, E., Cox, A., Janssen, M., Kruger, T.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Birth control
Embryo Transfer
Female
Fertilization in Vitro
Gynecology. Andrology. Obstetrics
human
Humans
in-vitro fertilization
infertility
Infertility, Male - therapy
Male
Medical sciences
Pregnancy
Prognosis
Prospective Studies
sperm morphology
Spermatozoa - abnormalities
Sterility. Assisted procreation
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Summary:A prospective randomized study was conducted to assess the prognostic value of sperm morphology in an in-vitro fertilization (IVF) programme, using strict criteria. The first group (T, teratozoospermic) included 32 couples with an isolated teratozoospermia in the male partner (morphology 9% normal, strict criteria). In both groups, 50 IVF cycles were performed. Patients were matched for indication for IVF. There was no difference between the two groups regarding age, duration of infertility, stimulation protocol, catheter used for embryo transfer and different sperm parameters. A statistically significant difference between the T and C groups respectively was observed regarding the fertilization rate (69.2 and 79.4%P < 0.05), pregnancy rate per cycle (12.0 and 42%, P < 0.001), the pregnancy rate per transfer (13.9 and 42.0%, P< 0.01) and per embryo transferred (6.1 and 14.8%, P< 0.05). No pregnancy occurred in the poor prognosis group (morphology
ISSN:0268-1161
1460-2350
DOI:10.1093/oxfordjournals.humrep.a138734