Lessons learned from interlaboratory comparisons of bioassay data interpretation

When a set of bioassay data is given to two different dosimetrists, it is likely that these data will be interpreted differently, that different methods and dosimetric models will be applied and therefore different numerical values will be obtained. Thus, it is important for laboratories dealing wit...

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Bibliographic Details
Published in:Radiation protection dosimetry 2003-01, Vol.105 (1-4), p.427-432
Main Authors: Doerfel, H., Andrasi, A., Bailey, M., Berkovski, V., Castellani, C.-M., Hurtgen, C., Jourdain, J.-R., LeGuen (INVITED), B.
Format: Article
Language:English
Subjects:
Benchmarking - methods
Biological and medical sciences
Computer Simulation
Cooperative Behavior
Europe
Humans
Interinstitutional Relations
Medical sciences
Models, Biological
Observer Variation
Occupational Exposure - analysis
Radiation Dosage
Radiation Protection - methods
Radiation Protection - standards
Radiation Protection - statistics & numerical data
Radioactive Pollutants - analysis
Radioisotopes - analysis
Radioisotopes - pharmacokinetics
Radiometry - methods
Radiometry - standards
Radiometry - statistics & numerical data
Reproducibility of Results
Sensitivity and Specificity
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Summary:When a set of bioassay data is given to two different dosimetrists, it is likely that these data will be interpreted differently, that different methods and dosimetric models will be applied and therefore different numerical values will be obtained. Thus, it is important for laboratories dealing with internal dosimetry to undergo performance testing procedures such as interlaboratory comparisons of bioassay data interpretation. Several intercomparison exercises have already been organised at national and international levels. The largest one so far was the 3rd European Intercomparison Exercise on Internal Dose Assessment, which has been organised in the framework of the EULEP/EURADOS Action Group, 'Derivation of parameter values for application to the new model of the human respiratory tract for occupational exposure'. The most important lesson learned from these intercomparison exercises was the need to develop agreed guidelines for internal dose evaluation procedures to promote harmonisation of assessments between organisations and countries.
ISSN:0144-8420
1742-3406
DOI:10.1093/oxfordjournals.rpd.a006274