The Role of Thymus in the Appearance of Immunologic Effects of Low Dose Irradiation

Serum levels of thymic hormones decreased in persons exposed to low doses of ionising radiation after the Chernobyl accident. The probable causes of secretory deficiency of the thymus are increased production of autoantibodies reactive to thymic epithelial cells (hormone producers) and general hormo...

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Bibliographic Details
Published in:Radiation protection dosimetry 1995-10, Vol.62 (1-2), p.77-79
Main Authors: Yarilin, A.A., Sharova, N.I., Kuzmenok, O.I., Kotchergina, N.I., Nikonova, M.F., Litvina, M.M., Savina, N.P.
Format: Article
Language:English
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Summary:Serum levels of thymic hormones decreased in persons exposed to low doses of ionising radiation after the Chernobyl accident. The probable causes of secretory deficiency of the thymus are increased production of autoantibodies reactive to thymic epithelial cells (hormone producers) and general hormonal imbalance. The main consequence of the decrease of thymic hormone level is hypofunction of T cells displaying a decreased proliferative response on stimulation by various factors.
ISSN:0144-8420
1742-3406
DOI:10.1093/oxfordjournals.rpd.a082826