Chronic effects of fumonisin B1 in broilers and turkeys fed dietary treatments to market age

Floor pen studies were conducted with 270 broiler chicks and 144 turkey poults, all 1 wk old, to evaluate the chronic effects of fumonisin B1 (FB1). A completely randomized design was used in both studies with six pen replicates of 15 chicks or eight pen replicates of six poults assigned to each of...

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Bibliographic Details
Published in:Poultry science 2002-01, Vol.81 (1), p.56-61
Main Authors: Broomhead, J N, Ledoux, D R, Bermudez, A J, Rottinghaus, G E
Format: Article
Language:English
Subjects:
Animal Feed
Animals
Body Weight - drug effects
Chickens - physiology
Dose-Response Relationship, Drug
Feeding Behavior
Fumonisins - administration & dosage
Fumonisins - toxicity
Liver - drug effects
Liver - metabolism
Male
Organ Size - drug effects
Random Allocation
Species Specificity
Teratogens - toxicity
Turkeys - physiology
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Summary:Floor pen studies were conducted with 270 broiler chicks and 144 turkey poults, all 1 wk old, to evaluate the chronic effects of fumonisin B1 (FB1). A completely randomized design was used in both studies with six pen replicates of 15 chicks or eight pen replicates of six poults assigned to each of three dietary treatments from Weeks 1 to 7 (broilers) or to Week 14 (turkeys). Fusarium moniliforme (M-1325) culture material was added to a typical corn-soybean basal diet to supply 0, 25, or 50 mg FB1/kg diet. Feed intake, body weight gain, and feed conversion of chicks were not affected (P > 0.05) by FB1. Turkeys fed 50 mg FB1/kg had significantly (P < 0.05) lower feed intake than the controls. Compared with controls, chicks and turkeys fed FB1 diets had significantly higher liver sphinganine to sphingosine ratios (P < 0.05). Relative organ weights of chicks were not affected (P > 0.05) by FB1, other than those chicks fed 25 mg FB1/kg, which had lower (P < 0.05) relative proventriculus weights than the chicks fed 0 or 50 mg FB1/kg. Broilers fed 50 mg FB1/kg had decreased serum calcium and increased serum chloride when compared to broilers fed 0 or 25 mg FB1/kg. Hematology was not affected (P > 0.05) by dietary FB1. No lesions were present in any organ examined microscopically. Results indicate that 50 mg FB1/kg diet is detrimental to turkeys but is not toxic to broilers fed to market age.
ISSN:0032-5791
DOI:10.1093/ps/81.1.56