Chemistry of a Nigerian Herbal Preparation (Cow's Urine Concoction) I

Cow's urine concoction is a traditional herbal preparation commonly administered to convulsing children by the Yoruba-speaking people of Nigeria. Its use is, however, usually complicated by severe poisoning. Methylene chloride extracts from two samples of the preparation were analyzed by direct...

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Bibliographic Details
Published in:Journal of tropical pediatrics (1980) 1982-10, Vol.28 (5), p.235-239
Main Authors: AYORINDE, F. O., AVERY, J. W., ADEKILE, A. D., OJEWOLE, J. A., ODEBIYI, O. O.
Format: Article
Language:English
Subjects:
Animals
Cattle - urine
Humans
Magnoliopsida - analysis
Medicine, Traditional
Nigeria
Phytotherapy
Poisoning - etiology
Seizures - drug therapy
Urine - analysis
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Summary:Cow's urine concoction is a traditional herbal preparation commonly administered to convulsing children by the Yoruba-speaking people of Nigeria. Its use is, however, usually complicated by severe poisoning. Methylene chloride extracts from two samples of the preparation were analyzed by direct application of gas chromatography-mass spectrometry (gc-ms). Gas chromatographic traces indicated over fifty compounds, the major constituents include nicotine, p-cresol and benzoic acid. The toxicity of these compounds is correlated with the clinical features of cow's urine concoction poisoning.
ISSN:0142-6338
1465-3664
DOI:10.1093/tropej/28.5.235