Obesity‐related higher blood pressure is associated with augmented transduction of spontaneous muscle sympathetic nerve activity

Central obesity is associated with elevated adrenergic activity and arterial blood pressure (BP). Therefore, we tested the hypothesis that transduction of spontaneous muscle sympathetic nerve activity (MSNA) to BP, i.e., sympathetic transduction, would be augmented in central obesity (increased wais...

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Bibliographic Details
Published in:The FASEB journal 2022-05, Vol.36 (S1), p.n/a
Main Authors: Holwerda, Seth W., Gangwish, Megan E., Luehrs, Rachel E., Nuckols, Virginia R., Pierce, Gary L.
Format: Article
Language:English
Online Access:Get full text
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Summary:Central obesity is associated with elevated adrenergic activity and arterial blood pressure (BP). Therefore, we tested the hypothesis that transduction of spontaneous muscle sympathetic nerve activity (MSNA) to BP, i.e., sympathetic transduction, would be augmented in central obesity (increased waist circumference) and positively related to resting BP. Young/middle‐age obese (n=14) or non‐obese (n=14) adults without hypertension (average ambulatory 24‐hr BP
ISSN:0892-6638
1530-6860
DOI:10.1096/fasebj.2022.36.S1.R3174