Comparative analysis of mitochondrial CRC in permeabilized cells and isolated cell mitochondria

Mitochondria undergo permeability transition (PT) resulting in the opening of the non‐selective PT pores (PTPs) in the inner mitochondrial membrane in response to energy and oxidative stresses associated with Ca2+ overload and ROS accumulation. The mitochondrial PTPs are permeable to ions and solute...

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Bibliographic Details
Published in:The FASEB journal 2022-05, Vol.36 (S1), p.n/a
Main Authors: Jang, Sehwan, Chapa‐Dubocq, Xavier R., Fossati, Silvia, Javadov, Sabzali
Format: Article
Language:English
Online Access:Get full text
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Summary:Mitochondria undergo permeability transition (PT) resulting in the opening of the non‐selective PT pores (PTPs) in the inner mitochondrial membrane in response to energy and oxidative stresses associated with Ca2+ overload and ROS accumulation. The mitochondrial PTPs are permeable to ions and solutes with a molecular mass
ISSN:0892-6638
1530-6860
DOI:10.1096/fasebj.2022.36.S1.R4561