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Interaction between fructooligosaccharides (FOS) and dietary lipids: Effects on mineral absorption and balance, bone mass and biomechanical properties in rats
Fructooligosaccharides (FOS) stimulate the mineral absorption in the large intestine, which increases bone mineral retention. Changes in lipid composition have been related to changes on fluidity of enterocytes brush border membranes. Our hypothesis was that dietary lipid composition might influence...
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Published in: | The FASEB journal 2006-03, Vol.20 (4), p.A196-A196 |
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Main Authors: | , , , , , |
Format: | Article |
Language: | English |
Online Access: | Get full text |
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Summary: | Fructooligosaccharides (FOS) stimulate the mineral absorption in the large intestine, which increases bone mineral retention. Changes in lipid composition have been related to changes on fluidity of enterocytes brush border membranes. Our hypothesis was that dietary lipid composition might influence the effects of FOS on the intestinal absorption of Ca, Mg, Fe and Cu, and some bone characteristics. Male rats (n=24) were fed a 15% lipid diet (soy oil or a 1:0.3 mix of fish and soy oils) or diets containing the same lipid sources supplemented with 10% FOS (Raftilose® Synergy 1) for 15 days. Feces and urine were collected for the evaluation of mineral absorption and balance. At sacrifice, the cecum contents and walls were weighed and the pH was determined in situ. Femurs were collected for Ca analyses (AAS) and bone strength evaluation (3‐point bending assay). FOS consumption resulted in an increase (p |
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ISSN: | 0892-6638 1530-6860 |
DOI: | 10.1096/fasebj.20.4.A196-b |